Virtual meeting: instructions to connect are communicated upon registration.

Human reproductive health and fertility is dependent on gonadotropins (FSH &LH), which act through their specific G protein-coupled receptors (GPCR) and regulate the reproductive functions. Gonadotropin hormone imbalance may contribute to the development of sub-fertility or infertility such as seen in women with polycystic ovary syndrome (PCOS), the most common endocrinopathy and a threat to human reproduction. The usage of ART/IVF has increased all over the world to restore sub-fertility in young women.

With the emerging role of gonadotropins (FSH and LH), It is important to understand the mechanisms of gonadotropin signaling, especially for delineating the metabolic defects due to their imbalance (high LH:FSH ratio) in women with PCOS, menopause and gynaecological cancers. It is further imperative to increase the positive outcome of IVF protocols to deal with the sub-fertility in young women due to PCOS or other environmental factors.

This interdisciplinary conference will discuss the current challenges in the targeting of GPCRs and finding novel pathways to optimize not only reproduction but also metabolism, and to discuss their role as non-gonadal ligands. 

This international conference is organised in the framework of the ARD CVL BIOPHARMACEUTICALS Programme.

Topics

• Gonadotropin Signaling
• G protein-coupled receptors
• Metabolism
• Physiopathology
• Therapeutics

• Prof. Rita Singh, LE STUDIUM Visiting Researcher
  FROM: University of Delhi - IN
  IN RESIDENCE AT: Physiology of Reproduction and Behaviour (PRC) / Centre INRAe Val de Loire, CNRS, University of Tours, IFCE - FR​
• Dr Pascale Crépieux, 
  Physiology of Reproduction and Behaviour (PRC) / Centre INRAe Val de Loire, CNRS, University of Tours, IFCE - FR

​Scientific advisors

Dr Eric Reiter & Dr Frédéric Jean-Alphonse
Physiology of Reproduction and Behaviour (PRC) / Centre INRAe Val de Loire, CNRS, University of Tours, IFCE - FR