Ion channel signaling in health and disease

June 23, 2025 - June 26, 2025
Conference

Château Belmont
57 rue Groison
37100 Tours
France

Presentation

Ion channels and Calcium signaling fulfill the most critical functions in all eukaryotic cells. They underlie electrical signals central to sensory, cognitive, cardiac, endocrine and exocrine functions. They mediate critical signal transduction pathways that touch every aspect of life,  from development, muscle contraction, secretion,  release of neurotransmitters, hormones, metabolic activity, gene transcription, memory, pain sensation, fertilization, cell differentiation, cell migration and programmed cell death. This meeting will showcase the latest insights and discoveries in the field of ion channels and Ca2+ signaling in particular. 

This is a rapidly evolving area of research, which has a high translational impact as a diverse array of diseases  are causally linked to disruptions in ion channel activities. In fact, gain and loss of function of ion channels is directly linked to diseases ranging from neuronal, cardiovascular, immune, kidney and endocrine diseases to various types of cancer. Ion channels, also offer significant potential as targets for personalized therapies due to their considerable functional and structural diversity.

Convenors

Mohamed Trebak, LE STUDIUM Visiting Researcher

FROM University of Pittsburgh - USA
IN RESIDENCE AT Niche, Nutrition, Cancer & Oxidative metabolism (N2COX) / INSERM, University of Tours - FR

Marie Potier-Cartereau & Christophe Vandier
Niche, Nutrition, Cancer & Oxidative metabolism (N2COX) / INSERM, University of Tours - FR

 

Scientific Committee

  • Patrick G. Hogan, La Jolla Institute - CA USA
  • Richard S. Lewis, Stanford University - CA USA
  • Mark T. Nelson, University of Vermont - VT USA
  • Marie Potier-Cartereau, University of Tours, France
  • Murali Prakriya, Northwestern University, IL USA
  • L. Fernando Santana, University of California Davis, CA USA
  • Mohamed Trebak , University of Pittsburgh, PA USA
  • Christophe Vandier, University of Tours, France

  Location

Chateau_Belmont

 

Château Belmont :
57, Rue Groison - 37100 TOURS - FR

Château Belmont, an establishment steeped in history, welcomes you to a 17th-century building surrounded by 2.5 hectares of parkland. Once planted with vines renowned for their south-facing aspect, the château became a hospital during the 1870 war.
After the war, Baroness Tellier de Blanrier acquired the property in 1880 and had the ceiling of the living room painted. In 1885, the vines were replaced by apple trees, which produced cider for over sixty years.
Passionate about flowers, the next owners decided to turn the estate into a tulip research centre.
In 1987, Jean and Sophie Bardet opened a restaurant. Jean Bardet, a renowned chef, offered creative, gourmet and refined cuisine.
The AEGIDE-Domitys group opened its first hotel in 2008, bringing Château Belmont to life.
Discover this place steeped in history, where the elegance of the past blends harmoniously with modern comforts. Treat yourself to an unforgettable stay in an enchanting setting, steeped in the richness and charm of its prestigious past.

How to get there ?

Train By train:

* Tours centre station
 1.5 hour trip from Paris (Montparnasse)

 * Saint Pierre des Corps (4km from Tours town centre)

Bus 5, 20 minutes trip to Tours centre station

> Plan your trip by train: https://www.sncf-connect.com/en-en/

 

By tramway:

20 minutes trip from Tours centre station

> Take Tramway A in direction to Vaucanson, step out at Tranchée stop

Château Belmont is an 8-minute walk from the stop.

 

By bus:

25 minutes trip from Tours centre station

> Take Bus 10 in direction to Beffroi, step out at Charles Barrier stop

Château Belmont is an 9-minute walk from the stop.

Voiture By car:

GPS: 47.4079083,0.6871076
Please note that you can't park in the courtyard in front of the Château Belmont.
Paid car park nearby : 
Parking Relais: Tranchée - Fil Bleu, 16 Rue des Bordiers, 37100 Tours
 

Avion By plane:

*Arrival at Roissy Charles De Gaulle (CDG) airport
Take RER B in direction to Saint Rémy Les Chevreuse, step out at Denfert Rochereau Stop
Metro 6 in direction to Charles de Gaulle Etoile, step out at Montparnasse Bienvenue Stop 

> Then take a train to Tours (see "by train" section above)

*Arrival at Paris-Orly (ORY) airport: 

Take Orlyval Shuttle from Aéroport d’Orly in direction Antony, step out at Antony Stop

Take RER B in direction to Mitry Clave, step out at Denfert Rochereau Stop

Take Metro 6 in direction to Charles de Gaulle Etoile, step out at Montparnasse Bienvenue Stop

> Then take a train to Tours (see "by train" section above)

 General Information

Information

Congress Venue

Château Belmont
57 rue Groison  - 37100 Tours, France

Dates

 Dates

Monday, 23 June to Thursday 26 June 2025

Language

 Language

The official language of the Congress is English

Badge

Welcome pack and Name Badge

 Upon arrival you will receive a welcome pack that includes the printed material of the Conference and your name badge will be given to you at the reception . Please wear your name badge at all times during the Conference and to all official Conference events.

Invitation Letters

Invitation Letters

 An official letter of invitation facilitating the obtention of an entry visa can be sent upon request . In order to receive an invitation letter for visa purposes, send an email to maurine.villiers@lestudium-ias.fr. Please note that : 
- we only issue an official letter once the payment of the registration fee has been validated.
- such letters do not represent a commitment on the part of the Organisers to provide any financial assistance.

Certificat

Certificate of attendance

 After the conference, in order to receive a certficate of participation, send an email to maurine.villiers@lestudium-ias.fr

Short talks & posters

Abstracts for short talk and poster should be submitted before Monday 28th April 2025.

Please upload your abstract during the registration or send it before the deadline to maurine.villiers@lestudium-ias.fr.

The number of oral presentations is limited, convenors will process a selection and confirm your presentation few days later.

Please note that we do not print the posters, but racks & pins will be provided for up to A0 sizes, portrait format.

Pricing

Registration will open shortly

(Including three lunches, a wine & cheese cocktail and wine cellar visit and the coffee breaks)

Private institutions 750 EUR
Public institutions 500 EUR
Students & PhD Scholars 200 EUR
Gala dinner 90 EUR

 

Cancellation Policy
All cancellations must be made in writing and sent by email to the Registration Department
Up to 30 days prior to conference start – Full refund less €50 handling fee
Less than 30 days prior to conference start – No refund

Confirmed speakers

  • David Julius, University of California-San Francisco, CA - USA
  • Bruce Bean, Harvard University, MA - USA
  • Holly Ingraham, University of California-San Francisco, CA - USA
  • Mark T. Nelson, University of Vermont, VT - USA
  • Richard S. Lewis, Stanford University, CA - USA
  • Murali Prakriya, Northwestern University, IL - USA
  • Patrick G. Hogan, La Jolla Institute, CA - USA
  • Anjana Rao, La Jolla Institute, CA - USA
  • L. Fernando Santana, University of California Davis, CA - USA
  • Mohamed Trebak, University of Pittsburgh, PA - USA
  • Marie Potier-Cartereau, University of Tours, FR
  • David I. Yule, University of Rochester, NY - USA
  • Scott Earley, University of Rochester, NY - USA
  • Jonathan H. Jaggar, University of Tennessee, TN - USA
  • Madeline Nieves-Cintron, University California-Davis, CA - USA
  • Martha Cyert, Stanford University, CA - USA
  • Rose Dixon, University of California-Davis, CA - USA
  • Jeffrey Holt, Harvard University, MA - USA
  • Alexander Sobolevsky, Columbia University, NY - USA
  • Medha Pathak, University of California-Irvine, CA - USA
  • Diana Bautista, University of California-Berkley, CA - USA
  • Eduardo Perozo, University of Chicago, IL - USA
  • Stefan Feske, New York University, NY - USA
  • Amy Lee, University of Texas Austin, TX - USA
  • Dejian Ren, University of Pennsylvania, PA - USA
  • Kenton Swartz, National Institutes of Health, MD - USA
  • Grace E. (Beth) Stutzmann, Chicago Medical School, IL - USA
  • Steven Marx, Columbia University, NY - USA
  • Nicolas Demaurex, University of Geneva - CH
  • Khaled Machaca, Cornell University-Qatar - QA
  • Geert Bultynck, KU Leuven - BE
  • Michel De Waard, University of Nantes - FR
  • Olivier Soriani, University Cote D’azur, Nice - FR
  • Anna Gomez, INSERM, Châtenay-Malabry, FR
  • David E. Clapham, HHMI; Janelia Farms, VA - USA
  • Liang Feng, Stanford University, CA - USA
  • Seok-Yong Lee, Duke University, NC - USA
  • Mike Salter, University of Toronto, ON - CA
  • Zhaozhu Qiu, Johns Hopkins University, MD - USA
  • Jeanne Nerbonne, Washington University at St Louis, MO - USA

 

Tourist visits in Touraine :

 

Cathedrale_St_Gatien

Cathédrale Saint Gatien: This impressive cathedral boasts a facade adorned with detailed carvings and remarkable stained glass windows, a testament to flamboyant Gothic architecture. St-Gatien's Cathedral is open from 8.30am to 8pm every day of the week. It is located Place de la Cathédrale, 37000 Tours. You can reach them on 02 47 70 21 00.

Place_Plumereau

Place Plumereau: Situated in the heart of Vieux Tours, this lively square is surrounded by half-timbered houses and numerous cafés and restaurants, providing a friendly atmosphere in which to relax and observe local life.

Basilique_St_Martin_Rond

Basilique Saint Martin: An important place of pilgrimage, with its impressive architecture and crypt housing the saint's tomb. Saint Martin church is open from 7.15am to 7pm from Tuesday to Saturday. It is located 7 Baleschoux Street, 37000 Tours. You can reach them on 02 47 05 63 87.

Tour_Charlemagne

Charlemagne Tower : A real landmark in the town, the Charlemagne tower (and its neighbour, the Horloge tower) are the last remains of the medieval collegiate church of Saint-Martin, destroyed between 1798 and 1802. The Tour de l'Horloge (50m) was part of the main façade, while the Tour Charlemagne (56m) was the bell tower on the north arm of the transept. The Charlemagne Tower is open from Monday to Thursday (8.30am to 5pm) and Friday from 8.30am to 4.30pm. It is located 83 Halles Street, 37000 Tours. You can reach them on 02 47 21 61 88.

Musée_Histoire_Naturelle_Rond

Museum of Natural History of Tours : Located in the old town of Tours, just a stone's throw from Place Plumereau, the Natural History Museum offers permanent and temporary scientific exhibitions, as well as a vast vivarium area and a rich natural science documentation centre. The museum is open every day of the week from 9.30am to 12.30pm / 2pm to 6pm. It is located 3 President Merville Street, 37000 Tours. The museum is a 15-minutes walk from Tours station. You can reach them on 02 47 21 68 08. Full price €5 / Low price €2.50.

CCCOD_Rond

Le Centre de Création contemporaine Olivier Debré : Right in the heart of the Loire châteaux region, the CCC OD provides the city of Tours with a prestigious creative venue of international renown. It is open from Wednesday to Sunday, 11am to 6pm and Saturday until 7pm. You can contact them : 02 47 66 50 00 / contact@cccod.fr . Prices from €5.50 to €8.50.

 

 

Chateau
Castles :
Chateau de Chenonceau

Château de Chenonceau: Nicknamed the ‘Château des Dames’, it is famous for its elegant architecture spanning the Cher and its refined gardens. The Château de Chenonceau can be reached by train in 30 minutes from Tours station. The château is a 2-minute walk from Chenonceau station. It is possible to book tickets to visit on the website : https://www.chenonceau.com/ . The full adult fare is €18, €16 for students, €15 for children from 7 to 18 years old.

Chateau de Villandry

Château de Villandry: Known for its formal gardens, it offers an exceptional visual experience with its flower and vegetable beds. The castle is located 3 Main Street, 37510 Villandry. The castle is open from 9am to 6pm and gardens between 9am to 7pm. You can come by public transport from Tours with the bus for 1 hour. Information from the service provider: 02 47 66 70 70.

Forteresse_Royale_Chinon

Forteresse Royale de Chinon: This medieval castle offers a glimpse into French history and a breathtaking view of the River Vienne. It is located 2 Castle Street, 37500 Chinon. The forteresse is 40 minutes from Tours by car and 20 minute walk from Chinon station. It is open every day from 9.30am to 6pm. Prices range for €8.50 to €10.50.

Clos_Luce

Château du Clos Lucé: The last home of Leonardo da Vinci, it features models of his inventions and a park dedicated to his works. It is located 2 Clos Lucé Street, 37400 Amboise. It is open every day from 10am to 64pm. The castle is accessible by train from Tours Station to Amboise and you have to walk 25 minutes to reach the castle. A bus service runs between the station and Amboise town centre all year round. You can contact them at 02 47 57 00 73.

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