The contributor's responsibility involves the evaluation of optimized Epilobium extracts' bioactivity using advanced in vitro techniques on human keratinocytes and dermal fibroblasts. This comprehensive assessment will focus on determining the extracts’ antioxidant and anti-inflammatory effects, as well as their influence on the viability and proliferation of these skin cell types. Such analyses are essential for uncovering potential therapeutic applications of Epilobium extracts in dermatology, especially those that could contribute to innovative skincare solutions.