Anna Wawruszak
From
Medical University of Lublin - PL
In residence at
Host scientist
Catherine Grillon
BIOGRAPHY
Graduated from Maria Curie-Sklodowska University in Medical Biotechnology and Chemistry of Bioactive Agents and Cosmetics (master’s degree studies) in 2013 and 2014, respectively, and got her PhD at the Department of Biochemistry and Molecular Biology at the Medical University in Lublin in 2020. Since then she has been working at the Medical University of Lublin as a postdoc, researcher and, finally, a group leader (Associate Professor). Her primary expertise lies in translational medicine, epigenetics and breast cancer research. Her works are mainly focused on the anti-cancer activity of histone deacetylase inhibitors in breast cancer models. She has also an interest in green chemistry and biotechnology approaches for the development of nature-based cosmetics.
PROJECT
GreenCosmIn - green chemistry and biotechnology approaches for the development of nature-based cosmetics
GreenCosmIn aims to establish a robust, multisectoral, and interdisciplinary network to implement environmentally friendly approaches in the exploration and exploitation of natural resources, with a focus on cosmetics production. The project will assess the biological activity of selected lead extracts and/or isolated compounds using various platforms, including in vitro tools, with keratinocytes and melanoma monolayer and 3D models tested under different oxygen concentration conditions (normoxia/hypoxia). In vitro screening of extracts, fractions, or isolated/semisynthesized compounds will be conducted to evaluate their ability to inhibit specific enzymes relevant to cosmetic applications. Following treatment with natural products, parameters such as antioxidant activity, lipid peroxidation, skin aging, pigmentation, ROS production, or SOD catalase activity will be determined.
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This project has received funding from the Horizon Europe research and innovation programme under the Marie Skłodowska-Curie Staff Exchanges Action Grant Agreement No 101131346 |