Immuno - Neuro Modulation (INEM)

INEM studies the influence of exposome, including microbiota, on immuno-neuromodulation.  To do so, INEM investigates the mechanisms of injury- and infection-induced lung inflammation and immune response modulation, and the effects of early exposure to pollutants on neuropathology and neuro-inflammation.
INEM develops murine models of human diseases, associated with sophisticated technical in vivo and ex vivo investigations combining transcriptomic, proteomic and metabolomic analysis.

Research topics:

• Immune responses to infections and pollutants
• Allergy, infection, stress and Immunity
• Inflammation, danger signals, infection and pulmonary pathologies
• Environmental pollutants and Neurotoxicity
• Neuroinflammation
• Emerging theme: Microbiota & Pathophysiology
   

Equipment and technology :

•    Analysis of lung function by plethysmography
•    Access to TAAM animal facilities and germ-free isolators,
•    Histology and hematology,
•    Molecular and cellular biology; Multiplex,
•    Flow cytometry and fluorescence microscopy,
•    Behavioural analysis
•    Certified ISO9001:2015 LRQA