LE STUDIUM Multidisciplinary Journal

Chirality is a recurring cross-disciplinary theme in modern science, from particle physics to biology. In quantum physics, the chirality of fermions is linked to the topology of gauge fields by the chiral anomaly. While the chiral anomaly is usually associated with the short-distance behavior in field theory, recently, it has been realized that it also affects the macroscopic behavior of chiral matter. In particular, the local imbalance between left- and right-handed fermions in the presence of a magnetic field induces non-dissipative transport of electric charge ("the Chiral Magnetic Effect", CME). Recently, the CME has been discovered in Dirac and Weyl semimetals possessing chiral quasi-particles. Here we report on the investigation of related phenomena in non-centrosymmetric superconductors and Josephson junctions and discuss their potential applications in quantum computing.

Chirality is a recurring cross-disciplinary theme in modern science, from particle physics to biology. In quantum physics, the chirality of fermions is linked to the topology of gauge fields by the chiral anomaly. While the chiral anomaly is usually associated with the short-distance behavior in field theory, recently, it has been realized that it also affects the macroscopic behavior of chiral matter. In particular, the local imbalance between left- and right-handed fermions in the presence of a magnetic field induces non-dissipative transport of electric charge ("the Chiral Magnetic Effect", CME). Recently, the CME has been discovered in Dirac and Weyl semimetals possessing chiral quasi-particles. Here we report on the investigation of related phenomena in non-centrosymmetric superconductors and Josephson junctions and discuss their potential applications in quantum computing.

Plasma technology can be applied in different stages of agricultural production with increasing yield and improving quality. The promotion effect of plasma on agriculture depends on the plasma treatment parameters and effective methods of plasma diagnostics. In order to obtain optimized plasma treatment parameters and identify plasma agricultural objects, it is necessary to combine with artificial intelligence (AI), which can play an important role in plasma diagnosis and plasma agricultural applications. In our studies, plasma discharge spectra were effectively identified by building an AI model. In order to identify agricultural objects by plasma treatment at different stages of agricultural production, different AI models were constructed, showing the effectiveness of AI in plasma agriculture. These results also show the practical application and advantages of the plasma-agriculture-AI multidisciplinary combination. 

Two novel solid-state sodium battery electrolyte materials (a polymerised ionic liquid block co-polymer and a zwitterionic plastic crystal) have been characterised by high-field NMR spectroscopy. The results allow the identification of the Na+ solvation environment, which will determine the ion transport mechanism. Additionally, solid-electrolyte interphase products formed in sodium metal batteries containing two different ionic liquid electrolytes have been studied by the same experimental method and a breakdown product of the ionic liquid anion has been tentatively identified. These results demonstrate the power of NMR to provide new insights into sodium battery materials.

This project pursued a comparative examination of the Judeo-Spanish, French and Spanish translations of the lament Dos lid funem oysgehargetn Yidishn folk, written in the antechamber of Auschwitz by the Polish poet Yitzhak Katzenelson (1886-1944).
The study focused on the poetic forms and language of these translations, and offered a sociocultural perspective devoted to analyzing their role in the unearthing, symbolic as well as physical, of the Jewish voice and its reincorporation into the contemporary polyglot Jewish poetic archive. The research explored the intercultural and inter-historical relations that these translations produce, especially in the case of the Judeo-Spanish one and the glottopolitical role it plays when translating between endangered Jewish languages (Yiddish and Judeo-Spanish).
New knowledge was produced on the definition and practice of Jewish translation, its material culture and cultural transmission at the turn of the 20th century and the first decades of the 21st century. Also, light was shed on the epistemic recovery of the Jewish poetic archive through contemporary performances of memory making. In conclusion, this research proposed to recognize Jewish translation within the genre of postmemory.
 

The main goal of the project is the development of novel nanostructured carbon dots for their application as solar UV protectors in various materials, ranging from paints/varnishes to pharmaceutical/cosmetic products, which involve an entirely new approach in solar UV protection based on highly photoluminescent Carbon Dots (CDs) through efficient translation of the incident solar UV radiation towards longer wavelengths. The lower energy photons produced in the radiative processes within the CDs are less capable of inducing irreversible changes over the chemical/structural properties of the exposed surfaces. CDs are particularly suited for this approach due to their wide range UV excitation of the radiative processes, physico-chemical stability, inertness, lack of toxicity, biocompatibility and ease of fabrication. The provided UV protection is intended to be assayed upon their integration in various polymers matrices of relevance for coating materials and also targeting cosmetic skin UV protection formulations.

In oviparous animals such as birds, embryonic development occurs in the egg, and after oviposition there is no further possibility of material exchange with the hen to fulfill the needs of the embryo. In such a context, the egg must contain all systems required for proper development of a living organism. Among these, the chorioallantoic membrane (CAM) is a novel placenta-like structure which is the nexus for many different physiological and metabolic processes including acid-base balance, breathing and calcium solubilization from the eggshell that is re-allocated to assist bone and tissue formation in the embryo. Moreover, it is believed to play a pivotal role in innate immunity to protect the embryo, in close interaction with the eggshell and the eggshell membranes. Therefore, weakening of the eggshell during CAM-mediated decalcification is hypothesized to be compensated by upregulation of innate immune mechanisms. In order to characterize this role of the CAM during embryonic development, we performed transcriptomics, proteomics and bioinformatics analyses. This residence was also the opportunity to stimulate a new international dynamic collaboration towards investigating innate immunity in diverse biomineralized structures (shells, bone, corals). 

Insects are the most evolutionarily and ecologically successful group of living animals, being present in almost all possible mainland habitats; however, they are virtually absent in the ocean, which constitutes more than 99% of the Earth’s biosphere. Only a few insect species can be found in the sea but they remain at the surface, in salt marshes, estuaries, or shallow waters. Remarkably, a group of 13 species manages to endure long immersion periods in the open sea, as well as deep dives, i.e., seal lice. During the evolutionary transition of pinnipeds from land to the ocean, echinophthiriid seal lice had to manage the gradual change to an amphibian lifestyle along with their hosts, some of which may spend more than 80% of the time submerged and performing extreme dives, some beyond 2000 m under the surface. These obligate and permanent ectoparasites have adapted to cope with hypoxia, high salinity, low temperature, and, in particular, conditions of huge hydrostatic pressures. A major remainig question is whether or not seal lice do breath underwater or, on the contrary they dramatically reduce their metabolism to spare oxygen when submerged. During the reported period, we investigated anatomical adaptations to prolongued immersion and also set up a method for measuring oxigen consumption in two media, air and water in small insects, both using state of the art methods.

Several ex vivo and in vitro skin models are available in the toolbox of dermatological and cosmetic research. Some of them are widely used in drug penetration testing. The excised skins show higher variability, while the in vitro skins provide more reproducible data. The aim of the current study was to compare the chemical composition of different skin models (excised rat skin, human skin and human reconstructed epidermis) by measurement of ceramides, cholesterol, lactate, urea, protein and water at different dephts of the tissues. The second goal was to compile a testing system which includes a skin-on-a-chip diffusion setup and a confocal Raman spectroscopy for testing drug diffusion across the skin barrier and accumulation in the tissue models. A hydrophylic drug caffeine and the P-glycoprotein substrate quinidine were used in the study as a topical cream formulation. The results indicate that although the transdermal diffusion of quinidine is lower, the skin accumulation was similar for the two drugs. The different skin models allowed comparable permeability for both compounds, but chemical composition differed. The human skin was abundant in ceramides and cholesterol, while the reconstructed skin contained less water and more urea and protein. Based on these results it can be concluded that skin-chip and confocal Raman microspectroscopy are suitable for monitoring drug penetration and distribution in different skin layers during and at the end of exposure. Furthermore, the human skin obtained from obese patients is not the most relevant model for skin absorption testing in pharmaceutical research.

While International law is first said to be a distinct profession with institutions and journals in the 1870's, this project has shown that  from the Vienna Congress (1815) to the Franco-Prussian Wars (1870-1871), lawyers have initiated professional practices and shaped the making of International Law. They were involved in foreign offices, scientific academies, and universities, wrote textbooks and articles and created professional networks. This project investigates, for the first time, the interaction between foreign offices and international lawyers. This paper puts forward a prosopography of legal advisers employed in the French Ministry of Foreign Affairs and of the members of the Consultative Litigation Committee. Two peer-reviewed publications have been accepted and a conference proceeding is forthcoming.